Carcinogenesis

COMMENTARY:

Guido Frosina

Counteracting spontaneous transformation via overexpression of rate-limiting DNA base excision repair enzymes
Carcinogenesis 2001 22: 1335-1341; doi:10.1093/carcin/22.9.1335 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ACCELERATED PAPER:

Christopher J. Luscombe, Michael E. French, Samson Liu, Mark F. Saxby, Peter W. Jones, Anthony A. Fryer, and Richard C. Strange

Outcome in prostate cancer associations with skin type and polymorphism in pigmentation-related genes
Carcinogenesis 2001 22: 1343-1347; doi:10.1093/carcin/22.9.1343 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CANCER BIOLOGY:

Benjamin Chun Yu Wong, Wei Ping Wang, Chi Hin Cho, Xiao Ming Fan, Marie Chia Mi Lin, Hsiang Fu Kung, and Shiu Kum Lam

12-Lipoxygenase inhibition induced apoptosis in human gastric cancer cells
Carcinogenesis 2001 22: 1349-1354; doi:10.1093/carcin/22.9.1349 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Noriaki Sunaga, Takashi Kohno, Kazuya Shinmura, Takayuki Saitoh, Tomonari Matsuda, Ryusei Saito, and Jun Yokota

OGG1 protein suppresses G:CT:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells
Carcinogenesis 2001 22: 1355-1362; doi:10.1093/carcin/22.9.1355 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lorenza Tacchini, Paola Dansi, Emanuela Matteucci, and Maria Alfonsina Desiderio

Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells
Carcinogenesis 2001 22: 1363-1371; doi:10.1093/carcin/22.9.1363 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Keith R. Martin, Carol Trempus, Muriel Saulnier, Frank W. Kari, J.Carl Barrett, and John E. French

Dietary N-acetyl-L-cysteine modulates benzo[a]pyrene-induced skin tumors in cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) mice
Carcinogenesis 2001 22: 1373-1378; doi:10.1093/carcin/22.9.1373 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Wan-Lin Yang and Harold Frucht

Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells
Carcinogenesis 2001 22: 1379-1383; doi:10.1093/carcin/22.9.1379 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Agnes Schwieger, Lilian Bauer, Jörg Hanusch, Christine Sers, Reinhold Schäfer, and Georg Bauer

ras oncogene expression determines sensitivity for intercellular induction of apoptosis
Carcinogenesis 2001 22: 1385-1392; doi:10.1093/carcin/22.9.1385 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Xin Min Zhou, Benjamin Chun Yu Wong, Xiao Ming Fan, Hong Bo Zhang, Marie Chia Mi Lin, Hsiang Fu Kung, Dai Ming Fan, and Shiu Kum Lam

Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak
Carcinogenesis 2001 22: 1393-1397; doi:10.1093/carcin/22.9.1393 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

Wen Zhu, Jin-San Zhang, and Charles Y.F. Young

Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP
Carcinogenesis 2001 22: 1399-1403; doi:10.1093/carcin/22.9.1399 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Stefan Fronhoffs, Thomas Brüning, Elena Ortiz-Pallardo, Peter Bröde, Brigitte Koch, Volker Harth, Agapios Sachinidis, Hermann Maximillian Bolt, Claus Herberhold, Hans Vetter, and Yon Ko

Real-time PCR analysis of the N-acetyltransferase NAT1 allele *3, *4, *10, *11, *14 and *17 polymorphism in squamous cell cancer of head and neck
Carcinogenesis 2001 22: 1405-1412; doi:10.1093/carcin/22.9.1405 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Stephen Murray, Brian G. Lake, Stuart Gray, Anne J. Edwards, Christine Springall, Elizabeth A. Bowey, Gary Williamson, Alan R. Boobis, and Nigel J. Gooderham

Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man
Carcinogenesis 2001 22: 1413-1420; doi:10.1093/carcin/22.9.1413 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Joseph Przybyszewski, Ann L. Yaktine, Ellen Duysen, Darcy Blackwood, Weiqun Wang, Angela Au, and Diane F. Birt

Inhibition of phorbol ester-induced AP-1–DNA binding, c-Jun protein and c-jun mRNA by dietary energy restriction is reversed by adrenalectomy in SENCAR mouse epidermis
Carcinogenesis 2001 22: 1421-1427; doi:10.1093/carcin/22.9.1421 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Enikö Kallay, Peter Pietschmann, Shinya Toyokuni, Erika Bajna, Philipp Hahn, Karl Mazzucco, Christian Bieglmayer, Shigeaki Kato, and Heide S. Cross

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage
Carcinogenesis 2001 22: 1429-1435; doi:10.1093/carcin/22.9.1429 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Giuseppe Matullo, Domenico Palli, Marco Peluso, Simonetta Guarrera, Sonia Carturan, Egidio Celentano, Vittorio Krogh, Armelle Munnia, Rosario Tumino, Silvia Polidoro, Alberto Piazza, and Paolo Vineis

XRCC1, XRCC3, XPD gene polymorphisms, smoking and ³²P-DNA adducts in a sample of healthy subjects
Carcinogenesis 2001 22: 1437-1445; doi:10.1093/carcin/22.9.1437 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Panagiotis Georgiadis, Jan Topinka, Meni Stoikidou, Stella Kaila, Maria Gioka, Klea Katsouyanni, Radim Sram, Herman Autrup, and Soterios A. Kyrtopoulos

Biomarkers of genotoxicity of air pollution (the AULIS project): bulky DNA adducts in subjects with moderate to low exposures to airborne polycyclic aromatic hydrocarbons and their relationship to environmental tobacco smoke and other parameters
Carcinogenesis 2001 22: 1447-1457; doi:10.1093/carcin/22.9.1447 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENESIS:

Marcel Osterod, Stephan Hollenbach, Jan G. Hengstler, Deborah E. Barnes, Tomas Lindahl, and Bernd Epe

Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice
Carcinogenesis 2001 22: 1459-1463; doi:10.1093/carcin/22.9.1459 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carmel Mothersill, David Rea, Eric G. Wright, Sally A. Lorimore, Dennis Murphy, Colin B. Seymour, and Kiaran O'Malley

Individual variation in the production of a `bystander signal' following irradiation of primary cultures of normal human urothelium
Carcinogenesis 2001 22: 1465-1471; doi:10.1093/carcin/22.9.1465 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chow H. Lee and Anthony M. Edwards

Stimulation of DNA synthesis and c-fos mRNA expression in primary rat hepatocytes by estrogens
Carcinogenesis 2001 22: 1473-1481; doi:10.1093/carcin/22.9.1473 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Moreno Paolini, Alessandra Antelli, Laura Pozzetti, Denisa Spetlova, Paolo Perocco, Luca Valgimigli, Gian Franco Pedulli, and Giorgio Cantelli-Forti

Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats
Carcinogenesis 2001 22: 1483-1495; doi:10.1093/carcin/22.9.1483 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ling-Ling Hsieh, Pei-Feng Wang, I.-How Chen, Chun-Ta Liao, Hung-Ming Wang, Ming-Chi Chen, Joseph Tung-Chieh Chang, and Ann-Joy Cheng

Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese
Carcinogenesis 2001 22: 1497-1503; doi:10.1093/carcin/22.9.1497 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eiichi Yagi, J.Carl Barrett, and Takeki Tsutsui

The ability of four catechol estrogens of 17ß-estradiol and estrone to induce DNA adducts in Syrian hamster embryo fibroblasts
Carcinogenesis 2001 22: 1505-1510; doi:10.1093/carcin/22.9.1505 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michael A. Pereira, Paula M. Kramer, Philip B. Conran, and Lianhui Tao

Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c-myc gene and on their promotion of liver and kidney tumors in mice
Carcinogenesis 2001 22: 1511-1519; doi:10.1093/carcin/22.9.1511 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ivan Bièche, Béatrice Parfait, Sengül Tozlu, Rosette Lidereau, and Michel Vidaud

Quantitation of androgen receptor gene expression in sporadic breast tumors by real-time RT–PCR: evidence that MYC is an AR-regulated gene
Carcinogenesis 2001 22: 1521-1526; doi:10.1093/carcin/22.9.1521 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M.C. Chang, Y.S. Ho, P.H. Lee, C.P. Chan, J.J. Lee, L.J. Hahn, Y.J. Wang, and J.H. Jeng

Areca nut extract and arecoline induced the cell cycle arrest but not apoptosis of cultured oral KB epithelial cells: association of glutathione, reactive oxygen species and mitochondrial membrane potential
Carcinogenesis 2001 22: 1527-1535; doi:10.1093/carcin/22.9.1527 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Norah Defamie, Baharia Mograbi, Cyril Roger, Laurent Cronier, André Malassine, Françoise Brucker-Davis, Patrick Fenichel, Dominique Segretain, and Georges Pointis

Disruption of gap junctional intercellular communication by lindane is associated with aberrant localization of connexin43 and zonula occludens-1 in 42GPA9 Sertoli cells
Carcinogenesis 2001 22: 1537-1542; doi:10.1093/carcin/22.9.1537 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Edgar Rivedal and Hanne Opsahl

Role of PKC and MAP kinase in EGF- and TPA-induced connexin43 phosphorylation and inhibition of gap junction intercellular communication in rat liver epithelial cells
Carcinogenesis 2001 22: 1543-1550; doi:10.1093/carcin/22.9.1543 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masako Ochiai, Tsuneyuki Ubagai, Toshihiko Kawamori, Hiroshi Imai, Takashi Sugimura, and Hitoshi Nakagama

High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase
Carcinogenesis 2001 22: 1551-1555; doi:10.1093/carcin/22.9.1551 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

Ricky A. Sharma, Andreas Gescher, John P. Plastaras, Chiara Leuratti, Rajinder Singh, Barbara Gallacher-Horley, Elizabeth Offord, Lawrence J. Marnett, William P. Steward, and Simon M. Plummer

Cyclooxygenase-2, malondialdehyde and pyrimidopurinone adducts of deoxyguanosine in human colon cells
Carcinogenesis 2001 22: 1557-1560; doi:10.1093/carcin/22.9.1557 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rainer Franke, Andreas Gruska, Alessandro Giuliani, and Romualdo Benigni

Prediction of rodent carcinogenicity of aromatic amines: a quantitative structure–activity relationships model
Carcinogenesis 2001 22: 1561-1571; doi:10.1093/carcin/22.9.1561 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Prabu Devanesan, Richard J. Santen, Wayne P. Bocchinfuso, Kenneth S. Korach, Eleanor G. Rogan, and Ercole Cavalieri

Catechol estrogen metabolites and conjugates in mammary tumors and hyperplastic tissue from estrogen receptor- knock-out (ERKO)/Wnt-1 mice: implications for initiation of mammary tumors
Carcinogenesis 2001 22: 1573-1576; doi:10.1093/carcin/22.9.1573 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ERRATA:

B. Paulsson, F. Granath, J. Grawé, L. Ehrenberg, and M. Törnqvist

The multiplicative model for cancer risk assessment: applicability to acrylamide
Carcinogenesis 2001 22: 1577; doi:10.1093/carcin/22.9.1577 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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